| Cubs | 0 | Brewers | 0 | Top 2 |
| 18:10 | Orioles | Albert Suárez | 1-0 2.35 | @ | Reds | Hunter Greene | 1-2 3.63 | ||
| 18:40 | Giants | Jordan Hicks | 2-0 1.59 | @ | Phillies | Aaron Nola | 4-1 3.20 | ||
| 18:40 | Rockies | Cal Quantrill | 0-3 5.34 | @ | Pirates | Martín Pérez | 1-1 2.86 | ||
| 18:45 | Blue Jays | Yusei Kikuchi | 2-2 2.94 | @ | Nationals | Patrick Corbin | 0-3 6.82 | ||
| 18:50 | Mets | Jose Quintana | 1-2 3.48 | @ | Rays | Aaron Civale | 2-2 5.06 | ||
| 19:05 | Tigers | Casey Mize | 1-0 3.08 | @ | Yankees | Marcus Stroman | 2-1 3.69 | ||
| 19:10 | Angels | José Soriano | 0-4 4.76 | @ | Guardians | Tanner Bibee | 2-0 3.45 | ||
| 19:40 | Rangers | Michael Lorenzen | 2-1 4.24 | @ | Royals | Brady Singer | 2-1 2.62 | ||
| 20:10 | Red Sox | Chase Anderson | 0-1 5.52 | @ | Twins | Chris Paddack | 2-1 5.88 | ||
| 20:10 | Mariners | George Kirby | 3-2 4.18 | @ | Astros | Ronel Blanco | 3-0 1.65 | ||
| 20:15 | White Sox | Jonathan Cannon | 0-1 7.24 | @ | Cardinals | Sonny Gray | 3-1 1.16 | ||
| 21:40 | Padres | Dylan Cease | 3-2 2.78 | @ | Diamondbacks | Zac Gallen | 3-2 3.38 | ||
| 21:40 | Marlins | Ryan Weathers | 2-2 4.55 | @ | Athletics | JP Sears | 1-2 4.64 | ||
| 22:10 | Braves | Charlie Morton | 2-0 3.60 | @ | Dodgers | Gavin Stone | 2-1 4.68 |