| Mets | 0 | Dodgers | 0 | Top 1 |
| 18:35 | Red Sox | Brayan Bello | 5-2 4.04 | @ | Orioles | Grayson Rodriguez | 5-1 3.20 | ||
| 18:40 | Pirates | Jared Jones | 3-4 3.05 | @ | Tigers | Tarik Skubal | 6-1 2.25 | ||
| 18:40 | Cardinals | Kyle Gibson | 3-2 3.81 | @ | Reds | Andrew Abbott | 3-4 2.68 | ||
| 18:50 | Athletics | Mitch Spence | 3-2 4.09 | @ | Rays | Zack Littell | 2-2 3.42 | ||
| 19:20 | Nationals | Jake Irvin | 2-5 3.79 | @ | Braves | Max Fried | 4-2 3.38 | ||
| 19:40 | Cubs | Ben Brown | 1-1 3.20 | @ | Brewers | Freddy Peralta | 3-3 3.81 | ||
| 19:40 | Blue Jays | Kevin Gausman | 3-3 4.47 | @ | White Sox | Mike Clevinger | 0-3 6.75 | ||
| 19:40 | Royals | Cole Ragans | 4-3 3.34 | @ | Twins | Simeon Woods Richardson | 1-0 2.57 | ||
| TBD | Dodgers | Gavin Stone | 4-2 3.60 | @ | Mets | Jose Quintana | 1-4 5.13 | ||
| 20:05 | Diamondbacks | Brandon Pfaadt | 2-3 4.05 | @ | Rangers | Dane Dunning | 3-3 4.43 | ||
| 20:40 | Guardians | Triston McKenzie | 2-3 3.44 | @ | Rockies | Ryan Feltner | 1-4 5.07 | ||
| 21:38 | Yankees | Nestor Cortes | 3-4 3.29 | @ | Angels | Griffin Canning | 2-4 5.05 | ||
| 21:40 | Astros | Hunter Brown | 1-5 7.06 | @ | Mariners | Luis Castillo | 4-6 3.44 | ||
| 21:40 | Marlins | Jesús Luzardo | 2-3 4.14 | @ | Padres | Matt Waldron | 2-5 4.86 | ||
| 21:45 | Phillies | Zack Wheeler | 6-3 2.53 | @ | Giants | Sean Hjelle | 1-1 3.26 |