| Date | Status | Player | Injury | Target Return? | Prognosis |
|---|
| 2024-09-24 | 60-Day IL | Esteury Ruiz | Arthroscopic knee surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-21 | 60-Day IL | Daulton Varsho | Shoulder surgery (rotator cuff) | 2024-12-11 | Out for 2024 season |
| 2024-09-20 | 60-Day IL | Will Wagner | Knee surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-18 | 60-Day IL | Sam Hentges | Shoulder surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-14 | 60-Day IL | Ben Gamel | Fractured leg (fibula) | 2024-12-11 | Out for 2024 season |
| 2024-09-14 | 60-Day IL | José Marte | Shoulder surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-13 | 60-Day IL | Corey Seager | Sports hernia surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-10 | 60-Day IL | Miguel Andujar | Core muscle surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-06 | 60-Day IL | Jo Adell | Strained oblique | 2024-12-11 | Out for 2024 season |
| 2024-09-03 | 60-Day IL | Javier Báez | Arthroscopic hip surgery | 2024-12-11 | Out for 2024 season |
| 2024-09-01 | 60-Day IL | Max Kepler | Knee tendinitis | 2024-12-11 | Out for 2024 season |
| 2024-08-30 | 60-Day IL | Jon Gray | Foot discomfort | 2024-12-11 | Out for 2024 season |
| 2024-08-28 | 60-Day IL | Jorge Mateo | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-08-25 | 60-Day IL | Matt Moore | Strained forearm | 2024-12-11 | Out for 2024 season |
| 2024-08-20 | 60-Day IL | Alex Faedo | Strained shoulder | 2024-12-11 | Out for 2024 season |
| 2024-08-20 | 60-Day IL | Jimmy Lambert | Shoulder surgery | 2024-12-11 | Out for 2024 season |
| 2024-08-19 | 60-Day IL | Yimi García | Elbow inflammation | 2024-12-11 | Out for 2024 season |
| 2024-08-18 | 60-Day IL | Tyler Mahle | Shoulder tightness | 2024-12-11 | Out for 2024 season |
| 2024-08-16 | 60-Day IL | José Soriano | Arm fatigue | 2024-12-11 | Out for 2024 season |
| 2024-08-14 | 60-Day IL | Dominic Leone | Sprained elbow | 2024-12-11 | Out for 2024 season |
| 2024-08-14 | 60-Day IL | Brock Stewart | Arthroscopic shoulder surgery | 2024-12-11 | Out for 2024 season |
| 2024-08-11 | 60-Day IL | James Paxton | Strained calf | 2024-12-11 | Out for 2024 season |
| 2024-08-07 | 60-Day IL | Luis Medina | Sprained elbow | 2024-12-11 | Out for 2024 season |
| 2024-08-07 | 60-Day IL | Joe Ryan | Strained shoulder (teres major) | 2024-12-11 | Questionable for 2024 season |
| 2024-08-07 | 60-Day IL | Mike Trout | Knee surgery (torn meniscus) | 2024-12-11 | Out for 2024 season |
| 2024-08-06 | 60-Day IL | Luis Rengifo | Wrist surgery | 2024-12-11 | Out for 2024 season |
| 2024-08-01 | 60-Day IL | Mike Clevinger | Neck surgery (disc replacement) | 2024-12-11 | Out for 2024 season |
| 2024-07-26 | 60-Day IL | Alex Wood | Arthroscopic shoulder surgery | 2024-12-11 | Out for 2024 season |
| 2024-07-14 | 60-Day IL | Chris Paddack | Strained forearm | 2024-12-11 | No timetable for return |
| 2024-07-13 | 60-Day IL | Isaiah Campbell | Elbow inflammation | 2024-12-11 | Out for 2024 season |
| 2024-07-13 | 60-Day IL | Andrew Wantz | Elbow surgery | 2024-12-11 | Out for 2024 season |
| 2024-07-03 | 60-Day IL | Jordan Romano | Arthroscopic elbow surgery | 2024-12-11 | Out for 2024 season |
| 2024-07-02 | 60-Day IL | J.P. France | Shoulder surgery (capsule tear) | 2024-12-11 | Out for 2024 season |
| 2024-06-26 | 60-Day IL | Oliver Ortega | Elbow surgery (loose body removal) | 2024-12-11 | Out for 2024 season |
| 2024-06-26 | 60-Day IL | Patrick Sandoval | Elbow surgery (UCL) | 2024-12-11 | Out for 2024 season |
| 2024-06-19 | 60-Day IL | Kyle Bradish | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-06-18 | 60-Day IL | Brendan White | Strained elbow | 2024-12-11 | Out for 2024 season |
| 2024-06-17 | 60-Day IL | Cole Winn | Shoulder discomfort | 2024-12-11 | No timetable for return |
| 2024-06-17 | 60-Day IL | Tyler Wells | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-06-17 | 60-Day IL | Alek Manoah | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-06-11 | 60-Day IL | Alex Kirilloff | Back discomfort | 2024-12-11 | No timetable for return |
| 2024-06-07 | 60-Day IL | Max Stassi | Hip surgery (surfacing procedure) | 2024-12-11 | Out for 2024 season |
| 2024-06-06 | 60-Day IL | Cristian Javier | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-06-05 | 60-Day IL | José Urquidy | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-06-03 | 60-Day IL | John Means | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-05-30 | 60-Day IL | Garrett Whitlock | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-05-26 | 60-Day IL | Evan Carter | Lower back tightness | 2024-12-11 | Out for 2024 season |
| 2024-05-18 | 60-Day IL | Sam Haggerty | Torn Achilles' tendon | 2024-12-11 | Out for 2024 season |
| 2024-05-15 | 60-Day IL | Ken Waldichuk | Tommy John surgery/ flexor tendon surgery | 2024-12-11 | Out for 2024 season |
| 2024-05-08 | 60-Day IL | Matt Brash | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-05-08 | 60-Day IL | Daniel Duarte | Elbow surgery (UCL revision) | 2024-12-11 | Out for 2024 season |
| 2024-05-02 | 60-Day IL | Jacob Waguespack | Strained shoulder | 2024-12-11 | Rehab assignment (9/6) |
| 2024-04-30 | 60-Day IL | Robert Stephenson | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-04-22 | 60-Day IL | Sawyer Gipson-Long | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-04-14 | 60-Day IL | Jonathan Loáisiga | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-04-12 | 60-Day IL | Shane Bieber | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-04-10 | 60-Day IL | Chris Murphy | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-04-03 | 60-Day IL | Bennett Sousa | Thoracic outlet syndrome surgery | 2024-12-11 | Out for 2024 season |
| 2024-04-03 | 60-Day IL | Trevor Gott | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-03-29 | 60-Day IL | Anthony DeSclafani | Elbow/Flexor tendon surgery | 2024-12-11 | Out for 2024 season |
| 2024-03-15 | 60-Day IL | Jackson Kowar | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2024-03-14 | 60-Day IL | Trevor Stephan | Elbow surgery (UCL) | 2024-12-11 | Questionable for 2024 season |
| 2024-03-13 | 60-Day IL | Kelvin Caceres | Strained lat | 2024-12-11 | No timetable for return |
| 2024-03-12 | 60-Day IL | Lucas Giolito | Elbow surgery (internal brace) | 2024-12-11 | Out for 2024 season |
| 2024-03-12 | 60-Day IL | Josh Taylor | Biceps soreness | 2024-12-11 | Rehab assignment (9/7) |
| 2024-02-14 | 60-Day IL | James Karinchak | Shoulder inflammation | 2024-12-11 | Rehab assignment (9/5) |
| 2024-01-14 | 60-Day IL | Kendall Graveman | Shoulder surgery | 2024-12-11 | Questionable for 2024 season |
| 2023-10-11 | 60-Day IL | Kyle Wright | Shoulder surgery (torn capsule) | 2024-12-11 | Out for 2024 season |
| 2023-10-09 | 60-Day IL | Félix Bautista | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2023-08-21 | 60-Day IL | Shane McClanahan | Tommy John surgery | 2024-12-11 | Questionable for 2024 season |
| 2023-08-02 | 60-Day IL | Liam Hendriks | Tommy John surgery | 2024-12-11 | Rehab assignment (8/18) |
| 2023-06-14 | 60-Day IL | Penn Murfee | Elbow surgery (UCL) | 2024-12-11 | No timetable for return |
| 2023-06-13 | 60-Day IL | Lance McCullers Jr. | Elbow surgery (flexor tendon/bone spur) | 2024-12-11 | Doubtful for 2024 season |
| 2023-05-19 | 60-Day IL | Luis Garcia | Tommy John surgery | 2024-12-11 | Out for 2024 season |
| 2023-05-03 | 60-Day IL | Lou Trivino | Tommy John surgery | 2024-12-11 | No timetable for return |
| 2023-04-12 | 60-Day IL | JT Brubaker | Tommy John surgery | 2024-12-11 | Rehab assignment (9/15) |