San Diego Padres third baseman Manny Machado has been activated off the paternity leave list on Friday. That is great news after Machado missed a few games earlier in the week due to a personal matter. He's batting fourth and covering third base during Friday's game against the Philadelphia Phillies. In a corresponding move, infielder Matthew Batten has been optioned to the minors. Fantasy managers should make sure to get Machado back in their lineups.

Tampa Bay Rays outfielder Josh Lowe (oblique) reportedly is feeling great during his minor-league rehab assignment. The 26-year-old says he's ready to return whenever the teams feels like bringing him back. In six games, Lowe is slashing .227/.346/.364 with a homer, and five RBI during his rehab stint. It sounds like Lowe is ready to return and could be activated off the injured list any day now.

Tampa Bay Rays relief pitcher Colin Poche (back) has been placed on the 15-day injured list on Friday. The move is retroactive to April 24th with Poche dealing with back tightness. The organization has not given a timetable for how long Poche will be sidelined. This is a hit to the Rays bullpen with Pete Fairbanks already sidelined as well. The loss of these two pitchers should mean increased save chances for Jason Adam and Garrett Cleavinger.

Chicago White Sox general manager Chris Getz said that outfielder Luis Robert Jr. (hip) should be back soon, perhaps by mid-May. Until that day comes, the White Sox plan to have a platoon in center field between Tommy Pham and Rafael Ortega. Robert is rehabbing from a Grade 2 right hip-flexor strain and was given a timetable of six weeks when he was put on the injured list back on April 6. The oft-injured 26-year-old Cuban outfielder needs to remain stashed in an IL spot in all fantasy leagues, though, after making the All-Star team in 2023 and clubbing a career-high 38 home runs, driving in 80 and stealing 20 bases in 145 games. Pham, 36, went 5-for-17 with two stolen bases for Triple-A Charlotte and is worthy of a waiver-wire pickup in deep-mixed leagues for his modest power and stolen base contributions.

Los Angeles Dodgers manager Dave Roberts said that right-hander Walker Buehler (elbow) will make another minor-league rehab start with Triple-A Oklahoma City next Tuesday. If all goes well, Buehler will then be activated to make his 2024 debut with the Dodgers. The 29-year-old hasn't pitched in a major-league game since 2022, but he got up to 86 pitches in 4 1/4 innings in his latest rehab start on Wednesday at Oklahoma City despite giving up five runs (three earned). His numbers on his rehab start have been nothing to write home about -- a 4.86 ERA, 1.68 WHIP, 16 strikeouts and nine walks in 16 2/3 innings -- but the most important thing is that he's healthy. Buehler could have some ups and downs early on with LA, but if he can show any of his pre-injury form in 2024, he has the potential to be a huge fantasy asset down the stretch.

Los Angeles Angels infielder Brandon Drury (knee) is back in the starting lineup on Friday against the visiting Minnesota Twins and right-hander Bailey Ober, serving as the designated hitter and batting fifth. Miguel Sano is at third base for the Halos and is hitting cleanup. Drury didn't start at all during the recent three-game series against the Baltimore Orioles due to a knee injury but appeared on Wednesday late in the game and struck out in his only plate appearance. Fantasy managers in deeper leagues will be hoping that Drury can show some signs of life at the plate this weekend, as he's started the 2024 season with a weak .194/.270/.269 slash line with a home run and four RBI in 74 plate appearances. He's never faced Ober in his career.

Milwaukee Brewers veteran left-hander Wade Miley (elbow) needs Tommy John surgery and will spend the next 10 to 12 months rehabbing and then decide whether to continue his career. It's a tough break for the 37-year-old southpaw and the Brewers. Fantasy baseball managers that were stashing Miley in deeper leagues can now officially let go. "I've always said I want to go out on my own [terms]," Miley said. "I still feel like I've got more in the tank." While it sounds like the 14-year veteran wants to give it a shot to come back at some point in 2025, it's fair to wonder if he's already thrown his final pitch in the big leagues. Even if Miley rehabs for a comeback next season, he'll be off the radar in most fantasy formats. The former 43rd overall pick by the Arizona Diamondbacks in 2008 out of Southeastern Louisiana gave up five earned runs with four walks and two K's in his two starts in 2024.

Cleveland Guardians second baseman Andres Gimenez is not in the club's starting lineup on Friday for the start of a big series in Atlanta against the Braves. With Gimenez starting on the bench, Gabriel Arias will start at the keystone and will hit seventh in the order against Braves left-hander Chris Sale. Gimenez is hitting a modest .258 (24-for-93) on the year with no home runs, 14 RBI and three stolen bases in his first 24 games. The left-handed hitter is surprisingly hitting better against southpaws (.280) in 29 plate appearances than he is against righties (.250), but he'll still get the day off against the lefty Sale. Arias has gone 14-for-50 with a homer, eight RBI and two steals early on but is hitless in his two career at-bats versus Sale.

Atlanta Braves outfielder Jarred Kelenic is out of the starting lineup on Friday with the team facing a left-handed pitcher. Veteran Adam Duvall will instead get the start in left field and will bat ninth against the visiting Cleveland Guardians and left-hander Logan Allen. Kelenic is hitting a strong .314 (16-for-51), although he has yet to clear the fences and has driven in only three runs in his first year in Atlanta. He's also only had one plate appearance against a southpaw this year, so fantasy managers should continue to expect him to sit regularly when Atlanta opposes a lefty. Duvall is a career .233 hitters against lefties in 921 plate appearances with 47 homers and 132 RBI. He has two home runs on the season but is a low-upside DFS play in the nine-hole against a pitcher he's never faced in his career.

Washington Nationals manager Dave Martinez wants to ease catcher Keibert Ruiz in now that he's returned from a bad case of influenza that caused him to lose 18-20 pounds. It will also give the skipper the opportunity to keep catcher Riley Adams' bat in the lineup on a regular basis after he posted a .793 OPS when he caught 11 of the last 13 games with Ruiz out. "We're definitely going to use him," Martinez said. "One, let him catch. And two, we can also DH Keibert like we've done in the past and let him continue to catch. He's done a great job. He's learned a lot over the years. He's really coming into his own. It's good to have him, to watch him play and to watch him get better every day he's out there." As long as the 27-year-old continues to play several times a week, he'll be valuable in two-catcher fantasy leagues.

Washington Nationals third baseman Nick Senzel (illness) remains under the weather on Friday against the Miami Marlins and is not in the starting lineup. Rookie Trey Lipscomb will get the nod at the hot corner and will hit out of the eight-hole against Marlins right-hander Anthony Maldonado, who will be making his major-league debut. Senzel was scratched from Thursday's lineup, so this will be his second straight missed game. Fantasy managers in deeper leagues will want to check back on Saturday to see if Senzel is feeling well enough to play. The 28-year-old opened the year on the injured list and has only five hits (two home runs) in his first 25 at-bats with the Nationals. Lipscomb has gone 11-for-53 (.208) with a homer, four RBI and four steals in his first 16 big-league games this year.

New York Mets right-hander Tylor Megill (shoulder) is scheduled to start a minor-league rehab assignment on Saturday and throw two innings for High-A Brooklyn. Megill is getting close to returning to the big leagues while recovering from a right-shoulder strain that he suffered during his season debut on March 31 against the Milwaukee Brewers. The 28-year-old will probably need more than one rehab start before the Mets activate him from the injured list. When fully healthy, Megill should have a spot in New York's starting rotation, making him worth a deep-league pickup for pitching depth. He ended up making 25 starts for the Mets in 2023 and held a 4.70 ERA (4.96 FIP) and 1.57 WHIP with a career-high 105 strikeouts and 58 walks in 126 1/3 innings pitched.

New York Yankees designated hitter J.D. Martinez (back) is hitting fifth in his debut with the team on Friday against the visiting St. Louis Cardinals and right-hander Miles Mikolas. Martinez is getting a late start to the 2024 campaign after signing with the team late in March. The 36-year-old veteran then tweaked his back while playing in extended spring training, further delaying his debut. Martinez is back now, though, and will give first baseman Pete Alonso more protection in the lineup. Martinez hit a strong .271/.321/.572 with 33 home runs with the Los Angeles Dodgers in 2023, and while he can still provide some decent pop in mixed fantasy leagues, nobody should be expecting him to be quite that good in New York. The Mets plan to ease Martinez back in, so don't be surprised to see him get frequent days of rest.

The Miami Marlins placed left-hander Jesus Luzardo (elbow) on the 15-day injured list (retroactive to April 23) on Friday with left-elbow tightness and recalled right-hander Anthony Maldonado from Triple-A Jacksonville in a corresponding move. The Marlins scratched Luzardo from his start on Friday against the Washington Nationals, and now he's going to miss at least the next two weeks. The 26-year-old southpaw first felt pain in his elbow while playing catch on Thursday but doesn't think he'll be out for too long. We should know more after the Marlins reveal the results of the tests on Luzardo's left arm. Maldonado is the team's No. 18 prospect, per MLB Pipeline, but he hasn't gone more than two innings in any of his minor-league appearances this year and is likely to be sent back to Jacksonville after his major-league debut on Friday.

Minnesota Twins right-hander Bailey Ober will look to keep rolling on Friday when he hits the road for a matchup with the Los Angeles Angels. The towering 6-foor-9 righty was lit up for eight earned runs in just 1 1/3 innings in his season debut on March 31 but has since allowed all of two earned runs over his last three starts spanning 17 innings of work. He dominated the Tigers over his last two starts, tossing 12 innings of one-run ball by allowing just five hits and one walk against nine punchouts. He still owns a 4.91 ERA due to his first start of the season but he also sports a 3.98 SIERA and has walked just 5.3% of the hitters he has faced. He'll take on an Angels team that is tied for 19th with a .319 wOBA on the season.

St. Louis Cardinals right-hander Miles Mikolas will look to get straightened out when he takes the ball for a road contest against the New York Mets. The 35-year-old was knocked around for nine hits, including three homers, leading to five earned runs allowed in just 4 1/3 innings in a losing effort against the Brewers his last time out. It was the second consecutive outing and third of five on the season in which the veteran has allowed five earned runs in less than five innings this season. The rough outing raised his ERA to 6.49 through five starts, although his 4.05 xFIP, 4.28 SIERA, and solid 6% BB% suggest positive regression is likely moving forward.

Toronto Blue Jays right-hander Chris Bassitt will be looking to get back into the win column for the third time this season on Friday versus the visiting Los Angeles Dodgers. The veteran took a tough-luck loss his last time out after tossing 5 1/3 innings of two-run ball but also allowed six hits and three walks against the Padres his last time out. While the 35-year-old owns a solid 3.90 ERA on the season, he also sports a 4.77 FIP and a 4.47 SIERA that both suggest some regression could be on the horizon. Of course, there's at least a decent chance of that happening on Friday against a Dodgers offense that ranks second in baseball with a .348 wOBA on the season.

The Chicago White Sox have selected veteran outfielder Tommy Pham from Triple-A Charlotte. Fellow outfielder Kevin Pillar has been designated for assignment in order to clear a spot on the active roster. The White Sox agreed to a minors pact with Pham just a week ago and are bringing him up after he appeared in four games with Charlotte. Pham had a nice season in 2023, hitting .256 with 16 home runs and 22 stolen bases alongside a .774 OPS across 129 games between the Mets and Diamondbacks. Pham interestingly had to settle for a minors pact despite the quality season as he could once again become fantasy-relevant if his power and speed remain in his age-36 season.

New York Mets designated hitter J.D. Martinez (back) is set to make his debut with the team on Friday against the visiting St. Louis Cardinals. He's expected to give All-Star first baseman Pete Alonso more protection in the batting order after hitting 33 home runs in just 479 plate appearances in 2023 with the Los Angeles Dodgers. However, Martinez won't be hitting behind Alonso every day, at least not to start. Manager Carlos Mendoza said the team will ease Martinez into regular playing time, which makes sense given his age (36) and the fact he dealt with a back injury while ramping up this spring. Fantasy managers can't expect another 30-plus homer season from Martinez while getting a late start to the year, but he can provide notable pop in mixed leagues if he can stay healthy.

Detroit Tigers catcher Carson Kelly (rib cage) has been scratched from Friday's starting lineup against the visiting Kansas City Royals with left rib-cage soreness. He will be available off the bench, however. In his place, Jake Rogers will start behind the plate and will bat eighth against Royals right-hander Seth Lugo. The fact that Kelly is available off the bench means that his injury probably isn't very serious, so the 29-year-old backstop could have a chance to return for Saturday's contest. The former second-round pick of the St. Louis Cardinals in 2012 is hitting just .205 (9-for-44) on the year with a homer and six RBI for Detroit. Rogers has been even worse, going 6-for-45 (.133) with a homer and two RBI, so DFS gamers should look elsewhere at the catcher position on Friday.