Chicago White Sox relief pitcher John Brebbia (calf) is set to begin a rehab assignment with Triple-A Charlotte on Friday. The right-hander appears to be back on track after suffering a calf injury during a game two weeks ago. It's uncertain how many outings Brebbia will need before rejoining the big league bullpen. The assumption is that Brebbia should be back before or in early May. However, Brebbia is likely going to take a backseat to Michael Kopech who appears to be the primary closer in Chicago. Brebbia should still be used in high leverage spots, but probably won't offer the same fantasy value.

New York Yankees relief pitcher Nick Burdi (elbow) has been placed on the 15-day injured list on Friday. This is a tough blow to the Yankees bullpen that is already dealing with injuries. Burdi was pitching well as he hasn't allowed a run through 6 1/3 innings this season. The Yankees are hopeful that it'll be a minimal stint on the injured list for Burdi. In a corresponding move, right-hander Cody Morris has been recalled from Triple-A to take the spot on the active roster.

San Diego Padres first baseman Jake Cronenworth (calf) has returned to the starting lineup ahead of Friday's game against the Toronto Blue Jays. The 30-year-old has missed each of the last two games due to a minor right-calf issue. However, Cronenworth will be back in there at first base and batting third against right-hander Yariel Rodriguez on Friday. Fantasy managers should make sure to get Cronenworth back in their lineups.

Minnesota Twins closer Jhoan Duran (oblique) threw 21 pitches of live batting practice before Friday's game at Target Field against the Detroit Tigers and didn't feel any discomfort. Duran is close to embarking on a minor-league rehab assignment. "He was supposed to throw 20 and he wanted an extra one, so that tells you he's feeling good," manager Rocco Baldelli said. Once the 26-year-old goes on a rehab assignment, it might not be long before Duran is able to make his 2024 debut. He should be rostered in all fantasy formats despite getting a late start to the season. While Duran can be a high-end fantasy closer when he's healthy, don't be surprised if the Twins ease him into late-inning situations when he initially returns to the big-league bullpen.

Chicago Cubs outfielder Ian Happ (hamstring) was pulled in the seventh inning of Friday's win over the visiting Miami Marlins due to right-hamstring tightness, according to manager Craig Counsell. Happ's status for the rest of the weekend is now to be determined. Given the fact that Happ also missed time in spring training with a left-hamstring strain, fantasy managers should not be surprised at all if this ends up being an injured-list situation for the switch-hitting outfielder. For now, the 29-year-old should be considered day-to-day. There's a good chance he won't play on Saturday, but check back anyway to see if he's active. With Seiya Suzuki (oblique) already on the IL, the Cubbies would be down to Cody Bellinger, Mike Tauchman and rookie Alexander Canario in their outfield, although Garrett Cooper and Patrick Wisdom could also be used out there.

Houston Astros left-hander Framber Valdez (elbow) played catch on Friday, and manager Joe Espada said the hope is that Valdez could throw off a mound on Saturday or Sunday. Valdez is currently on the injured list while dealing with left-elbow inflammation, but there's no structural damage and he's already throwing again after being sidelined on April 9. The 30-year-old southpaw won't come off the IL when he's eligible next week, but a minor-league rehab assignment may not be far off. In the meantime, his fantasy managers will be hoping he'll return sometime in May. Keep Valdez stashed in all fantasy formats until then. The Dominican starter had picked up where he left off in 2023 through his first two starts before his elbow injury, giving up just three earned runs while striking out 10 in 12 1/3 innings.

Philadelphia Phillies manager Rob Thomson said that right-hander Taijuan Walker (shoulder) will make a third minor-league rehab start on Sunday for Triple-A Lehigh Valley. If Walker comes out of that outing without any setbacks, he's expected to rejoin the Phillies' starting rotation after that to make his 2024 debut. The Phillies aren't going to rush the 31-year-old veteran back into the fold, especially with Spencer Turnbull pitching well right now as he fills in for Walker. Fantasy baseball managers looking for extra rotation depth in deeper mixed leagues may want to consider picking Walker up now and stashing him. Walker's 4.83 xFIP last year shows he was pretty lucky to come away with a 4.38 ERA in his 31 starts in 2023. He'll be a matchup-based streamer once he returns to the majors.

Pittsburgh Pirates left-handed reliever Aroldis Chapman's suspension has been reduced to one game after he settled with the league. Chapman will serve his one-game suspension on Friday night against the Boston Red Sox and won't be available out of the bullpen. The league suspended the 36-year-old southpaw for getting into a confrontation with an umpire during Monday's game against the New York Mets. The Cuban hurler does have a save on the season but has also allowed four runs (three earned) on two hits while walking six and striking out 11 in 5 2/3 innings pitched so far in 2024. The seven-time All-Star isn't Pittsburgh's primary closer but he can still be useful for his strikeout numbers and holds in deeper fantasy leagues.

Atlanta Braves outfielder Jarred Kelenic is on the bench on Friday with the team facing a left-hander. With Kelenic starting on the bench, Adam Duvall will make the start in left field for Atlanta and hit sixth in the batting order versus Texas Rangers left-hander Andrew Heaney. It's not out of the ordinary for Kelenic to get benched against a left-handed pitcher and he could use the break right now after going 2-for-13 with six strikeouts in his last four games played. The 24-year-old former Seattle Mariner has otherwise enjoyed his time so far in Atlanta, going 14-for-39 (.359) but with no home runs and only three RBI to show for it in his first 14 games. Duvall is hitless in his two career at-bats against Heaney.

Oakland Athletics outfielder Esteury Ruiz is out of the starting lineup on Friday against the Cleveland Guardians with a right-hander on the mound. Ruiz has started just one of his four games since being recalled from Triple-A Las Vegas, and that one start came against a left-handed pitcher. The 25-year-old speedster has gone 2-for-7 with two home runs, three RBI, a stolen base and three runs scored since returning from the minors, but the A's apparently view him only as a platoon outfielder for now on the short side against lefties. Seth Brown, JJ Bleday and Lawrence Butler are starting from left field to right field across Oakland's outfield on Friday. For his speed alone, Ruiz is probably still worth keeping stashed as a bench option in deep-mixed fantasy leagues.

Pittsburgh Pirates third baseman Ke'Bryan Hayes (back) has returned from his back injury and is playing third base while hitting third on Friday in the series opener against the Boston Red Sox and right-hander Brayan Bello. Hayes is back in the lineup after missing the last two games with lower-back tightness. It obviously wasn't a serious issue for the 27-year-old, who will now look to get on track at the plate after an off day on Thursday. Hayes has hit .277 (18-for-65) in the early going but has yet to clear the fences and went 3-for-17 with five walks and six strikeouts in the previous five games before his back injury. Hayes has never faced Bello in his career.

Washington Nationals first baseman/outfielder Joey Gallo and third baseman Nick Senzel are both out of the starting lineup on Friday against the visiting Houston Astros. Joey Meneses is playing first base and batting sixth, while Ildemaro Vargas is at third base and hitting ninth against Astros right-hander Justin Verlander, who is making his 2024 debut after dealing with a right-shoulder injury this spring. Gallo started each of the team's previous 14 games and could use a break after hitting just .170 with three home runs to begin the year. Senzel began the year on the injured list and has gone 2-for-11 with a walk and three strikeouts in his first three games of the year. Meneses and Vargas have gone hitless against Verlander in their careers in just five combined at-bats.

Los Angeles Angels infielder Brandon Drury (hamstring) is back in the starting lineup on Friday against the Cincinnati Reds, serving as the designated hitter and batting fifth in the order. Luis Rengifo remains at second base and is batting seventh for the Halos. Drury missed the team's last three games with left-hamstring tightness but is back in action against his former team, the Reds. It's a good place for Drury to come alive with the bat in a hitter-friendly environment. So far in 2024 in his first 55 at-bats, Drury has been cold, picking up only 11 hits for a .200 batting average while hitting one home run, driving in three and scoring five runs. The Reds currently don't have a starter listed for Friday's contest yet.

New York Yankees infielder DJ LeMahieu (foot) said after undergoing an MRI exam on Thursday, doctors don't yet feel comfortable sending him on a minor-league rehab assignment. The hope is later this week he can start playing in games. When the 35-year-old is finally cleared, he's expected to begin a rehab assignment with Double-A Somerset. LeMahieu has yet to make his 2024 MLB debut with the Yankees after initially being expected to open the year as the team's regular third baseman. Manager Aaron Boone said that next Tuesday is now the target date for LeMahieu to begin his rehab assignment. Oswaldo Cabrera is starting at the hot corner for the Yankees on Friday against the visiting Tampa Bay Rays and left-hander Tyler Alexander.

The Colorado Rockies announced on Friday that they placed left-hander Kyle Freeland (elbow) on the 15-day injured list (retroactive to April 16) with a left-elbow strain and recalled right-hander Noah Davis from Triple-A Albuquerque in a corresponding move. Freeland injured his right, non-throwing shoulder on a slide into home plate as a pinch-runner earlier this week but is now dealing with a left-elbow injury. The 30-year-old southpaw could be out longer than just two weeks, depending on the exact nature of his elbow injury. It's unclear who will take Freeland's spot in the starting rotation, but it could be Davis. Freeland was scheduled to make his next start on Saturday against the Seattle Mariners. After a 13.21 ERA with eight walks and nine K's in his first four starts, fantasy managers in mixed leagues can drop him for now.

The Cincinnati Reds claimed infielder Livan Soto off waivers from the Baltimore Orioles on Friday and optioned him to Triple-A Louisville. To make room on the 40-man roster, the Reds transferred right-hander Tejay Antone (elbow) to the 60-day injured list. Soto will join his third team of the year after the Orioles designated him for assignment earlier this week. The 23-year-old Venezuelan infielder made his major-league debut in 2022 with the Los Angeles Angels and has hit .375/.414/.531 with a .946 OPS, one home run, nine RBI and a stolen base in just 22 games played the last two seasons in Anaheim. He has a .780 OPS in 32 at-bats this year for Triple-A Norfolk and will now head to Louisville to give the Reds some extra infield depth.

Boston Red Sox third baseman Rafael Devers (knee) is not in the starting lineup for Friday's series opener against the hosting Pittsburgh Pirates. The 27-year-old went for an MRI on his knee after leaving Wednesday's game against the Cleveland Guardians with discomfort but the test revealed nothing more than bone bruise. He is not expected to require a stint on the injured list. It's been a sluggish start to the season for the star third baseman who is hitting just .188 but also has two homers and a healthy 15.5% BB% across 58 trips to the plate. Fantasy manager should check back daily to see when Devers is able to return to the lineup.

The Oakland A's have activated Brent Rooker (abdomen) from the injured list and have optioned 22-year-old infielder Darell Hernaiz to Triple-A Las Vegas. Despite breaking out with 30 home runs in the 2023 season, Rooker was not being used as an everyday outfielder to begin the season. He has hit just .200 on his young season but has still clubbed a pair of home runs across his first eight games of the campaign. Rooker will likely see consistent playing time upon his return but the A's outfield has gotten more crowded with his return and the promotion of the hot-hitting Esteury Ruiz from Triple-A. The team also has Seth Brown, JJ Bleday, and Lawrence Butler roaming the outfield.

Cincinnati Reds corner infielder Jeimer Candelario remains out of the lineup on Friday versus the visiting Los Angeles Angels due to an illness. The veteran was scratched from Tuesday's lineup before sitting out Wednesday's series finale against the Seattle Mariners. Santiago Espinal will once again take over duties at the hot corner while hitting eighth against Angels left-hander Tyler Anderson. The 30-year-old does have a pair of homers on the young season but is also hitting just .190 with a 31.3% K% across his first 64 plate appearances in a Reds uniform. He set career highs with 22 home runs and eight stolen bases across 140 games between the Nationals and Cubs last season.

Atlanta Braves left-hander Chris Sale will be looking to bounce back from a rough outing when he takes on the visiting Texas Rangers on Friday. The veteran was touched up for five earned runs on six hits, including a homer, while walking three against seven strikeouts across seven innings in a loss to the Marlins his last time out. Despite the tough outing, Sale has been quit good early on in his Braves tenure. While his ERA has risen to 4.58, he also sports a 2.91 xFIP, 3.09 SIERA, and a healthy 21.1% K-BB% through his first three starts with Atlanta. He remains a quality fantasy asset whose injury woes are seemingly behind him.