San Francisco Giants starting pitcher Alex Cobb (hip, shoulder) has been held back from throwing activities the last few days as he's still experiencing soreness in his shoulder. He is scheduled to see Dr. Ken Akizuki Friday night. Cobb had been working his way back from a hip surgery he had in October and started to experience some setbacks after throwing a bullpen session a few weeks ago. The 36-year-old won't be eligible to come off the injured list until late May, but these setbacks may push his return further into June. This isn't the news the Giants wanted to hear after needing to put newly acquired Blake Snell on the 15-day injured list this week. Cobb will have a rotation spot available for him when he returns, but fantasy managers and Giants fans will need to exercise patience for a couple more months for that moment.

Los Angeles Angels third baseman Anthony Rendon (hamstring) said he has a high-grade partial tear of his left hamstring and doesn't have a timetable to return. The Angels placed Rendon on the 10-day injured list on Sunday, but the 33-year-old is certainly going to be out for an extended amount of time. Ever since signing a seven-year deal with the Halos, Rendon has mostly been in the trainer's room and has been one of the biggest disappointments in baseball after recording a league-high 126 RBI and a career-high 34 home runs in his final year with the Nationals in 2019. Before the injury, he was hitting .267 (20-for-75) with no homers, three RBI and three steals. We wouldn't blame you for dumping Rendon to the waiver wire at this point. Miguel Sano has been playing third since Rendon went down, but Brandon Drury could also see time there moving forward.

New York Yankees outfielder Giancarlo Stanton (rest) is out of the starting lineup ahead of Friday's game against the Milwaukee Brewers. This appears to be a routine rest day for the veteran slugger. Stanton has started in five straight games, so the team has decided to give the 34-year-old the night off. In the meantime, Aaron Judge will serve as the designated hitter while Trent Grisham will cover center field versus right-hander Colin Rea.

San Diego Padres third baseman Manny Machado has been activated off the paternity leave list on Friday. That is great news after Machado missed a few games earlier in the week due to a personal matter. He's batting fourth and covering third base during Friday's game against the Philadelphia Phillies. In a corresponding move, infielder Matthew Batten has been optioned to the minors. Fantasy managers should make sure to get Machado back in their lineups.

Milwaukee Brewers veteran left-hander Wade Miley (elbow) needs Tommy John surgery and will spend the next 10 to 12 months rehabbing and then decide whether to continue his career. It's a tough break for the 37-year-old southpaw and the Brewers. Fantasy baseball managers that were stashing Miley in deeper leagues can now officially let go. "I've always said I want to go out on my own [terms]," Miley said. "I still feel like I've got more in the tank." While it sounds like the 14-year veteran wants to give it a shot to come back at some point in 2025, it's fair to wonder if he's already thrown his final pitch in the big leagues. Even if Miley rehabs for a comeback next season, he'll be off the radar in most fantasy formats. The former 43rd overall pick by the Arizona Diamondbacks in 2008 out of Southeastern Louisiana gave up five earned runs with four walks and two K's in his two starts in 2024.

New York Yankees designated hitter J.D. Martinez (back) is hitting fifth in his debut with the team on Friday against the visiting St. Louis Cardinals and right-hander Miles Mikolas. Martinez is getting a late start to the 2024 campaign after signing with the team late in March. The 36-year-old veteran then tweaked his back while playing in extended spring training, further delaying his debut. Martinez is back now, though, and will give first baseman Pete Alonso more protection in the lineup. Martinez hit a strong .271/.321/.572 with 33 home runs with the Los Angeles Dodgers in 2023, and while he can still provide some decent pop in mixed fantasy leagues, nobody should be expecting him to be quite that good in New York. The Mets plan to ease Martinez back in, so don't be surprised to see him get frequent days of rest.

St. Louis Cardinals right-hander Miles Mikolas will look to get straightened out when he takes the ball for a road contest against the New York Mets. The 35-year-old was knocked around for nine hits, including three homers, leading to five earned runs allowed in just 4 1/3 innings in a losing effort against the Brewers his last time out. It was the second consecutive outing and third of five on the season in which the veteran has allowed five earned runs in less than five innings this season. The rough outing raised his ERA to 6.49 through five starts, although his 4.05 xFIP, 4.28 SIERA, and solid 6% BB% suggest positive regression is likely moving forward.

Toronto Blue Jays right-hander Chris Bassitt will be looking to get back into the win column for the third time this season on Friday versus the visiting Los Angeles Dodgers. The veteran took a tough-luck loss his last time out after tossing 5 1/3 innings of two-run ball but also allowed six hits and three walks against the Padres his last time out. While the 35-year-old owns a solid 3.90 ERA on the season, he also sports a 4.77 FIP and a 4.47 SIERA that both suggest some regression could be on the horizon. Of course, there's at least a decent chance of that happening on Friday against a Dodgers offense that ranks second in baseball with a .348 wOBA on the season.

The Chicago White Sox have selected veteran outfielder Tommy Pham from Triple-A Charlotte. Fellow outfielder Kevin Pillar has been designated for assignment in order to clear a spot on the active roster. The White Sox agreed to a minors pact with Pham just a week ago and are bringing him up after he appeared in four games with Charlotte. Pham had a nice season in 2023, hitting .256 with 16 home runs and 22 stolen bases alongside a .774 OPS across 129 games between the Mets and Diamondbacks. Pham interestingly had to settle for a minors pact despite the quality season as he could once again become fantasy-relevant if his power and speed remain in his age-36 season.

New York Mets designated hitter J.D. Martinez (back) is set to make his debut with the team on Friday against the visiting St. Louis Cardinals. He's expected to give All-Star first baseman Pete Alonso more protection in the batting order after hitting 33 home runs in just 479 plate appearances in 2023 with the Los Angeles Dodgers. However, Martinez won't be hitting behind Alonso every day, at least not to start. Manager Carlos Mendoza said the team will ease Martinez into regular playing time, which makes sense given his age (36) and the fact he dealt with a back injury while ramping up this spring. Fantasy managers can't expect another 30-plus homer season from Martinez while getting a late start to the year, but he can provide notable pop in mixed leagues if he can stay healthy.

San Diego Padres right-hander Yu Darvish (neck) threw a side session on Wednesday, after which "reports were favorable," according to manager Mike Shildt. "He was on the gas, but didn't have it to the floor... it was a positive first step." Darvish was put on the 15-day injured list on April 17 (retroactive to April 15) and last pitched on April 14 against the Los Angeles Dodgers. The 37-year-old was shut down in September of last year with a stress reaction in his right elbow and has dealt with back and neck issues in the past. It sounds like Darvish is improving, but at 37 years old, his recurring neck issue is something to keep an eye on when he returns. Before hitting the IL, he had a 4.18 ERA and 1.27 WHIP with 22 strikeouts and 10 walks in 23 2/3 frames over his first five starts.

San Diego Padres outfielder Jurickson Profar went 2-for-4 with a home run and a walk in Thursday's loss against the Colorado Rockies. Porfar took Nick Mears deep in the top of the seventh inning for his third homer of the season. The veteran has quietly been having a nice season for the Padres with a .295 batting average and 18 RBI. Profar should eventually regress, but he is worth riding while his bat is hot. For now, Profar is worth rostering, but managers would be wise to test the trade market and try to sell-high on the veteran. Profar will look to stay warm versus the division rival San Francisco Giants and Kyle Harrison on Friday evening.

Kansas City Royals catcher Salvador Perez came up clutch for his team during Thursday's game against the Toronto Blue Jays. The veteran catcher blasted a two-run home run off right-hander Jose Berries. That home run ended up being enough as the Royals won the game 2-0. The 33-year-old now has seven home runs on the year and is showing no signs of slowing down.

Chicago Cubs relief pitcher Hector Neris notched his third save on Thursday, slamming the door on the Houston Astros in a 3-1 win. Neris was a little shaky in his inning of work, walking a pair before getting out of it. Since manager Craig Counsell said that Adbert Alzolay was being taken out of the closer role last weekend, Neris has converted on all three of his save opportunities and apparently taken that role over. He should be added in most leagues where saves are important.

Philadelphia Phillies right-hander Zack Wheeler was brilliant on Thursday, tossing six shutout innings while allowing just one hit while punching out eight on the afternoon as part of a 5-0 win over the Cincinnati Reds. He walked four on the day and was at 103 pitches by the end of his outing but managed to earn his second decision of the season. With the outing, the 33-year-old lowered his ERA to a tidy 1.93 mark on the season through six starts, striking out 46 while walking 11 across 37 1/3 innings of work. Somehow, he has managed to go just 2-3 on the young season. He lines up to take on the Angels in his next scheduled start next Tuesday in Los Angeles.

Philadelphia Phillies first baseman Bryce Harper celebrated the birth of his second child with a home run on Thursday in his return from the paternity list. Harper's third-inning two-run shot was his fifth of the season and gave the Phillies a 4-0 lead as part of an eventual 5-0 victory over the Cincinnati Reds. Interestingly, Harper also homered in his first game back from the birth of his first child five years ago. The 31-year-old is now hitting .256 with those five long balls alongside 16 RBI and an .835 OPS across 22 games on the season. The two-time NL MVP has made a full-time transition to first base this season to take pressure off of his surgically-repaired elbow and has provided his typical big-time offense for fantasy managers early in the 2024 season.

Cleveland Guardians third baseman Jose Ramirez was 3-for-4 with a grand slam, stolen base and two runs scored during Thursday's 6-4 win over the Boston Red Sox. Ramirez smoked a ball to right field in the second inning after battling through a 10-pitch at-bat against Chase Anderson. The five-time All Star is now slashing .260/.271/.471 with five homers, 23 RBI, three stolen bases and 18 runs scored. He has had a more aggressive approach at the plate this season which has resulted in only two walks through 24 games. Despite the lower than normal OBP, Ramirez seems to be recovering nicely from a slower start to the year and remains one of the best third-base options in fantasy.

Colorado Rockies outfielder Charlie Blackmon is not in the starting lineup for Thursday's afternoon contest against the visiting San Diego Padres. It's not surprising to see the club give the veteran a spell in an afternoon game following an evening game on Wednesday in which Blackmon led off as the designated hitter and went 0-for-4 with a strikeout in his club's 5-2 loss. The 37-year-old is off to a sluggish start this season, hitting .228 with one homer, one stolen base, and a .659 OPS across 86 trips to the plate. At this point, Blackmon's power and speed just aren't there and he should be left on the waiver wire in all fantasy formats, including NL-only leagues.

The Philadelphia Phillies reinstated first baseman Bryce Harper from the paternity list on Thursday and optioned infielder Kody Clemens to Triple-A Lehigh Valley in a corresponding move after Wednesday's game. Harper is playing first base and batting third in his return in the series finale against the Cincinnati Reds and right-hander Nick Martinez on Thursday. Fantasy baseball managers will want to put the two-time MVP back in their starting lineups in all formats. He's hitless in two career at-bats against Martinez. The seven-time All-Star returns to a .241/.330/.443 slash line with four home runs, four doubles, 14 RBI, one stolen base and 10 runs scored in 91 plate appearances over his first 21 games of 2024. Harper will be hoping to extend his current six-game hitting streak in his return on Thursday.

Texas Rangers starting pitcher Max Scherzer threw two-and-a-third innings for Triple-A Round Rock on Wednesday, allowing three earned runs on five hits (two home runs), no walks, and four strikeouts. The veteran threw 52 pitches, which was the expectation heading into the game. The 39-year-old will likely make at least one more start, working his way up to 60-70 pitches next time out, before rejoining the Rangers at some point in May. Scherzer was solid in 2023's regular season, going 13-6 with a 3.77 ERA (3.77 SIERA), and a 1.12 WHIP, but his K-BB% of 20.8% was his lowest since 2014. He had a rough postseason, going 0-1 with a 6.52 ERA, 1.66 WHIP, and a 4.8% K-BB% over three starts. Hopefully he's able to shake off the rust and get back to form, both for the Rangers and for fantasy managers.