| Astros 8 Red Sox 3 - Final |
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| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | Tot |
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| Bos | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 3 |
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| Hou | 0 | 1 | 0 | 0 | 4 | 0 | 0 | 3 | x | 8 |
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Boston at Houston - Sat 23-Apr-2016 |
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| Red Sox Pitchers | IP | H | HR | K | BB | IBB | HB | ER | Win | L | Sav | WHIP | ERA | FIP |
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| Clay Buchholz | | 5.67 | 6 | 1 | 6 | 1 | 0 | 1 | 5 | 0 | 1 | 0 | 1.235 | 7.94 | 4.34 |
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| Tommy Layne | | 0.33 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.000 | 0.00 | 6.10 |
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| Noé Ramirez | | 0.33 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 9.000 | 0.00 | 12.10 |
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| Roenis Elías | | 1.67 | 4 | 0 | 1 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 3.600 | 16.20 | 3.70 |
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| Total | 8.00 | 12 | 1 | 8 | 5 | 1 | 1 | 8 | 0 | 1 | 0 | 2.125 | 9.00 | 4.60 |
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| Astros Pitchers | IP | H | HR | K | BB | IBB | HB | ER | Win | L | Sav | WHIP | ERA | FIP |
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| Mike Fiers | | 5.33 | 5 | 0 | 6 | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 1.312 | 3.38 | 1.98 |
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| Will Harris | | 0.67 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 | 0.00 | 3.10 |
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| Pat Neshek | | 1.00 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.000 | 0.00 | 1.10 |
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| Ken Giles | | 1.00 | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.000 | 9.00 | 1.10 |
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| Josh Fields | | 1.00 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.000 | 0.00 | 1.10 |
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| Total | 9.00 | 9 | 0 | 9 | 2 | 0 | 0 | 3 | 1 | 0 | 0 | 1.222 | 3.00 | 1.77 |
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